RNase III CLASH in MRSA uncovers sRNA regulatory networks coupling metabolism to toxin expression

RNase III CLASH in MRSA uncovers sRNA regulatory networks coupling metabolism to toxin expression

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Regulatory small RNA (sRNA) Artificial plant interact with mRNAs to regulate their stability, transcription, and translation via diverse mechanisms.Here, McKellar et al.apply RNase IIICLASH of multi-drug resistant Staphylococcus aureus under different culture conditions to link the network of RNA-RNA interactions to environmental conditions and find that the production of small membrane-permeabilizing toxins NORMAL/OILY HAIR CONDITIONER is strongly regulated by sRNAs.